A mura compensation method for display panel is disclosed, including: storing a specific grayscale compensation data table in a timing controller, in which the specific grayscale compensation data table is used for performing grayscale compensation to a fixed mura area in the display panel; obtaining a current grayscale of the display panel; based on the specific grayscale compensation data table, performing grayscale compensation to the current grayscale of a pixel in the fixed mura area of the display panel.