The present invention relates to methods for transmitting a frame by grouping a plurality of wireless terminals in a multiuser based wireless communication system. The present invention includes a method for transmitting a frame by including information about multiple receiver terminals in a MAC frame, another method for transmitting a frame by allocating group addresses and then using a corresponding group address for frame transmission, and yet another method for transmitting a frame by using a unique group sequence number that is allocated to each group and group control information that contains bitmap information. The group control information is included in a destination address field of a MAC layer, or in a signal field of a physical layer, or in both the MAC layer and the physical layer.