Invention Grant
- Patent Title: Ultrasensitive high Q-factor AT-cut-quartz crystal microbalance femtogram mass sensor
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Application No.: US15810348Application Date: 2017-11-13
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Publication No.: US10830738B2Publication Date: 2020-11-10
- Inventor: Selemani Seif Mziray , Thomas Thundat , Kenneth Cadien
- Applicant: University of Alberta
- Agency: Blue Filament Law PLLC
- Main IPC: G01N29/24
- IPC: G01N29/24 ; G01N29/02 ; G01N29/036 ; G01N33/543 ; G01N29/22 ; C12Q1/04

Abstract:
A device for detecting environmental contaminants, diseases, and acute medical conditions related to heart failure identifies pathogens or troponins before infection or damage to heart muscles using an ultrasensitive high Q-factor AT-cut quartz crystal microbalance (QCM) that can measure from a single pg to a single fg. The device has a set of five disks of a QCM with a 10 mm diameter and a full coated bottom electrode, with an upper electrode with a center dot with different diameters labelled as 1 mm, 2 mm, 3 mm, 4 mm, and 5 mm. The full coating denoting an electrically continuous thickness of at last one monolayer. Measured parameters from the five disks include Q-factors, impedance, dissipation factors (D) and frequency shift (Δf). Q-factors are used to calculate the Allman deviation σ(τ) and measured frequencies are converted to mass sensitivity using the Sauerbrey mass sensitivity coefficient (K).
Public/Granted literature
- US20180143167A1 ULTRASENSITIVE HIGH Q-FACTOR AT-CUT-QUARTZ CRYSTAL MICROBALANCE FEMTOGRAM MASS SENSOR Public/Granted day:2018-05-24
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