This disclosure is directed to calibrating sensors for an autonomous vehicle. First sensor data and second sensor data can be captured by one or more sensors representing an environment. The first sensor data and the second sensor data can be associated with a grid in a plurality of combinations to generate a plurality of projected data. A number of data points of the projected data occupying a cell of the grid can be summed to determine a spatial histogram. An amount of error (such as an entropy value) can be determined for each of the projected data, and the projected data corresponding to the lowest entropy value can be selected as representing a calibrated configuration of the one or more sensors. Calibration data associated with the lowest entropy value can be determined and used to calibrate the one or more sensors, respectively.