Invention Grant
- Patent Title: Methods of treating pancreatic cancer using GPCR antagonists
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Application No.: US15719421Application Date: 2017-09-28
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Publication No.: US10849955B2Publication Date: 2020-12-01
- Inventor: Tijana Talisman , Sunetra Biswas
- Applicant: City of Hope
- Applicant Address: US CA Duarte
- Assignee: CITY OF HOPE
- Current Assignee: CITY OF HOPE
- Current Assignee Address: US CA Duarte
- Agency: Mintz, Levin, Cohn, Ferris, Glovsky and Popeo, P.C.
- Main IPC: A61K31/485
- IPC: A61K31/485 ; A61K38/08 ; A61K38/10 ; A61K38/12 ; A61K38/16 ; A61P1/18 ; A61P35/00 ; G01N33/574
Abstract:
Provided herein are, inter alia, compositions and methods for the treatment of cancer and inhibition of metastasis. The compositions include a μ-opioid receptor (MOR) polypeptide and a somatostatin receptor 2 (SSTR2) polypeptide, wherein the MOR polypeptide is bound to a MOR antagonist and the SSTR2 polypeptide is bound to a SSTR2 antagonist. The compositions and methods provided herein are, inter alia, useful to treat pancreatic cancer.
Public/Granted literature
- US20180153953A1 METHODS OF TREATING PANCREATIC CANCER USING GPCR ANTAGONISTS Public/Granted day:2018-06-07
Information query
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