Invention Grant
- Patent Title: Prostate specific membrane antigen binding protein
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Application No.: US15821498Application Date: 2017-11-22
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Publication No.: US10849973B2Publication Date: 2020-12-01
- Inventor: Robert Dubridge , Pui Seto , Patrick Baeuerle , Jeanmarie Guenot , Holger Wesche , Bryan D. Lemon , Richard J. Austin
- Applicant: Harpoon Therapeutics, Inc.
- Applicant Address: US CA South San Francisco
- Assignee: HARPOON THERAPEUTICS, INC.
- Current Assignee: HARPOON THERAPEUTICS, INC.
- Current Assignee Address: US CA South San Francisco
- Agency: Wilson Sonsini Goodrich & Rosati
- Main IPC: A61K39/00
- IPC: A61K39/00 ; A61K39/395 ; A61P35/00 ; A61K38/17 ; C07K16/30 ; C07K16/18 ; C07K16/28 ; A61K38/00

Abstract:
Disclosed herein are PSMA binding proteins with improved binding affinities, and robust aggregation profiles. Also described are multispecific binding proteins comprising a PSMA binding protein according to the instant disclosure. Pharmaceutical compositions comprising the binding proteins disclosed herein and methods of using such formulations are further provided.
Public/Granted literature
- US20180161428A1 Prostate Specific Membrane Antigen Binding Protein Public/Granted day:2018-06-14
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