Invention Grant
- Patent Title: Biaryl urea derivative or salt thereof and preparation process and use for the same
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Application No.: US16850882Application Date: 2020-04-16
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Publication No.: US10851050B2Publication Date: 2020-12-01
- Inventor: Yonghui Wang , Yafei Huang , Fazhi Yu , Ting Tang
- Applicant: FUDAN UNIVERSITY
- Applicant Address: CN Shanghai
- Assignee: FUDAN UNIVERSITY
- Current Assignee: FUDAN UNIVERSITY
- Current Assignee Address: CN Shanghai
- Priority: CN201610455177 20160622; CN201610455207 20160622
- Main IPC: C07C275/00
- IPC: C07C275/00 ; C07D213/55 ; C07C311/51 ; C07C311/08 ; C07C311/03 ; A61P1/00 ; A61K31/17 ; C07D213/71 ; A61P17/06 ; C07C381/10 ; A61K31/18 ; C07C311/47 ; A61P19/02 ; C07C275/32 ; C07D213/70 ; C07C317/32 ; A61P11/06 ; A61P29/00 ; C07D213/40 ; C07D231/12

Abstract:
The present disclosure discloses a biaryl urea RORγt inhibitor, and specifically relates to a biaryl urea derivative, as represented by formula I, with an RORγt inhibiting activity, and a preparation process thereof, and a pharmaceutical composition comprising the compound. Further disclosed is use of the compound for treating an RORγt-related disease.
Public/Granted literature
- US20200239411A1 BIARYL UREA DERIVATIVE OR SALT THEREOF AND PREPARATION PROCESS AND USE FOR THE SAME Public/Granted day:2020-07-30
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