Invention Grant
- Patent Title: Method for increasing ETEC CS6 antigen presentation on cell surface and products obtainable thereof
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Application No.: US16567190Application Date: 2019-09-11
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Publication No.: US10851140B2Publication Date: 2020-12-01
- Inventor: Nils Carlin , Ann-Mari Svennerholm , Joshua Tobias
- Applicant: Scandinavian Biopharma Holding AB
- Applicant Address: SE Solna
- Assignee: SCANDINAVIAN BIOPHARMA HOLDING AB
- Current Assignee: SCANDINAVIAN BIOPHARMA HOLDING AB
- Current Assignee Address: SE Solna
- Agency: Knobbe, Martens, Olson & Bear LLP
- Priority: SE1150821 20110912
- Main IPC: C12N1/20
- IPC: C12N1/20 ; A01N63/00 ; A61K48/00 ; A61K39/108 ; A61K39/00 ; A61K39/38 ; C07K14/245 ; G01N33/569 ; C12N15/70 ; A61K38/00
Abstract:
A method for increase the presentation of ETEC CS6 antigen on a cell surface, comprising the step of contacting cells expressing said antigen with an aqueous solution comprising 0.6-2.2 percent phenol by weight, such that the presentation of said antigen is increased by at least 100%. A method for the manufacture of a killed whole cell vaccine for immunization against CS6-expressing ETEC. Cells and vaccines obtainable by the above methods.
Public/Granted literature
- US20190389913A1 METHOD FOR INCREASING ETEC CS6 ANTIGEN PRESENTATION ON CELL SURFACE AND PRODUCTS OBTAINABLE THEREOF Public/Granted day:2019-12-26
Information query
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