Invention Grant
- Patent Title: Peptides derived from Lengsin (LGSN), complexes comprising such peptides bound to MHC molecules
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Application No.: US15777621Application Date: 2016-11-23
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Publication No.: US10851366B2Publication Date: 2020-12-01
- Inventor: Alex Powlesland , Maurits Kleijnen
- Applicant: IMMUNOCORE LIMITED , ADAPTIMMUNE LIMITED
- Applicant Address: GB Oxfordshire
- Assignee: IMMUNOCORE LIMITED
- Current Assignee: IMMUNOCORE LIMITED
- Current Assignee Address: GB Oxfordshire
- Agency: Fenwick & West LLP
- Agent Andrea Nichols
- Priority: GB1520589.1 20151123
- International Application: PCT/GB2016/053659 WO 20161123
- International Announcement: WO2017/089777 WO 20170601
- Main IPC: C07K16/40
- IPC: C07K16/40 ; C12N9/00 ; C07K14/47 ; G01N33/573 ; A61K38/00

Abstract:
The present invention relates to novel peptides derived from Lengsin (LGSN), complexes comprising such peptides bound to recombinant MHC molecules, and cells presenting said peptide in complex with MHC molecules. Also provided by the present invention are binding moieties that bind to the peptides and/or complexes of the invention. Such moieties are useful for the development of immunotherapeutic reagents for the treatment of diseases such as cancer.
Public/Granted literature
- US20180327736A1 PEPTIDES DERIVED FROM LENGSIN (LGSN), COMPLEXES COMPRISING SUCH PEPTIDES BOUND TO MHC MOLECULES Public/Granted day:2018-11-15
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