Invention Grant
- Patent Title: Modulation of SMN expression
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Application No.: US15565488Application Date: 2016-04-11
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Publication No.: US10851371B2Publication Date: 2020-12-01
- Inventor: Frank Rigo , C. Frank Bennett , Constantin Van Outryve D'Ydewalle , Charlotte J. Sumner
- Applicant: Ionis Pharmaceuticals, Inc. , The Johns Hopkins University
- Applicant Address: US CA Carlsbad US MD Baltimore
- Assignee: Ionis Pharmaceuticals, Inc.,The Johns Hopkins University
- Current Assignee: Ionis Pharmaceuticals, Inc.,The Johns Hopkins University
- Current Assignee Address: US CA Carlsbad US MD Baltimore
- Agency: McNeill Baur PLLC
- International Application: PCT/US2016/026928 WO 20160411
- International Announcement: WO2016/164896 WO 20161013
- Main IPC: C12N15/113
- IPC: C12N15/113 ; C07H21/02 ; C12Q1/68

Abstract:
Certain embodiments are directed to methods and compounds for inhibiting SMN-NAT, the natural antisense transcript of SMN. Such methods and compounds are useful for increasing expression of SMN in cells and animals.
Public/Granted literature
- US20180273943A1 MODULATION OF SMN EXPRESSION Public/Granted day:2018-09-27
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