- Patent Title: Molecular identification with subnanometer localization accuracy
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Application No.: US16071974Application Date: 2017-02-06
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Publication No.: US10851411B2Publication Date: 2020-12-01
- Inventor: Johannes B. Wöhrstein , Kalim Mir , Ralf Jungmann , Florian Schüder
- Applicant: Ludwig-Maximilians-Universität München
- Applicant Address: DE Munich US MA Cambridge
- Assignee: Ludwig-Maximilians-Universität München,XGenomes Corp.
- Current Assignee: Ludwig-Maximilians-Universität München,XGenomes Corp.
- Current Assignee Address: DE Munich US MA Cambridge
- Agency: Saliwanchik, Lloyd & Eisenschenk
- Priority: EP16154448 20160205
- International Application: PCT/EP2017/052548 WO 20170206
- International Announcement: WO2017/134303 WO 20170810
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C12Q1/6874 ; C12Q1/6869 ; C12Q1/6816 ; C12Q1/6834 ; C12Q1/6853 ; G01N21/64
Abstract:
The present invention relates to methods of determining the sequence of nucleotides in target nucleic acid molecules. Thus, the invention relates to methods of sub-unit sequencing. The methods comprise the use of identification nucleic acid detection entities which specifically hybridize to the target nucleic acid, bind identification tags and have localization tags transiently bind thereto.
Public/Granted literature
- US20190024165A1 MOLECULAR IDENTIFICATION WITH SUBNANOMETER LOCALIZATION ACCURACY Public/Granted day:2019-01-24
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