A system, method, and computer-readable medium are disclosed for performing a dynamic application optimization operation, comprising: instrumenting a plurality of system parameters of a client information handling system for monitoring; instructing a user to execute a particular application on the client information handling system; obtaining a plurality of samples of the plurality of system parameters; performing a machine learning operation using the plurality of samples of the plurality of system parameters, the machine learning operation training a machine learning model to generate a profile for the particular application and an operating mode of the particular application; applying the profile to the client information handling system to provide a new information handling system configuration, the new information handling system configuration optimizing the information handling system for the particular application.