Devices, methods, non-transitory computer readable media, and other embodiments are described for automatic gate-level functional safety (FS) analysis and associated circuit design operations. One embodiment involves accessing register transfer level (RTL) design data, and accessing a set of FS data associated with an initial circuit design describing one or more failure modes associated with a plurality of circuit elements, an associated FS design criterion for each failure mode of the one or more failure modes, and one or more associations between the plurality of circuit elements and the one or more failure modes. The embodiment then involves generating a gate-level netlist using the RTL design data, mapping the one or more associations between the plurality of circuit elements from the RTL design data and the one or more failure modes to the gate-level netlist, and generating an updated set of FS data using the mapping of the one or more associations to the gate-level netlist.