Systems and methods for providing environmental safety notifications in virtual, augmented, and mixed reality (xR) applications are described. In some embodiments, an Information Handling System (IHS) may include a host processor and a memory coupled to the host processor, the memory having program instructions stored thereon that, upon execution, cause the IHS to: receive an image from a Simultaneous Localization and Mapping (SLAM) camera configured to detect a location of a Head-Mounted Device (HMD) worn by a user during an xR application; identify a safety event based upon the image; and produce an xR object for display by the HMD, wherein the xR object indicates the safety event.