A vending machine has a cabinet internally defining a dispensing compartment that is closed by a front door and houses a plurality of dispensing trays, each of which supports a plurality of products and is slidably engaged in a guide device defined by a pair of elongated guides, each of which is coupled to the cabinet through a front tooth and a rear tooth and is provided with a retractable spring-loaded locking pin movable between a coupling position and a release position with respect to the cabinet.