Invention Grant
- Patent Title: Morpholino oligonucleotides useful in cancer treatment
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Application No.: US16522381Application Date: 2019-07-25
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Publication No.: US10857174B2Publication Date: 2020-12-08
- Inventor: Prakash Ambady , Jeffrey Wu , Edward Neuwelt
- Applicant: United States Government As Represented By The Department of Veterans Affairs , Oregon Health & Science University
- Applicant Address: US DC Washington US OR Portland
- Assignee: UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS,OREGON HEALTH & SCIENCE UNIVERSITY
- Current Assignee: UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS,OREGON HEALTH & SCIENCE UNIVERSITY
- Current Assignee Address: US DC Washington US OR Portland
- Agency: Ballard Spahr LLP
- Main IPC: C07H21/04
- IPC: C07H21/04 ; A61K31/711 ; A61K9/00 ; A61P35/00 ; A61K31/4162
Abstract:
Disclosed are morpholino oligonucleotides that can be used to silence expression of MGMT, pharmaceutical compositions that include said morpholino oligonucleotides, and methods of using said morpholino oligonucleotides in the treatment of cancer, particularly methods that involve the use of radiation to deliver said morpholino oligonucleotides.
Public/Granted literature
- US20200030357A1 Morpholino Oligonucleotides Useful In Cancer Treatment Public/Granted day:2020-01-30
Information query
