Invention Grant
- Patent Title: Treatment of HMGB1-mediated inflammation
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Application No.: US15532226Application Date: 2015-12-14
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Publication No.: US10857197B2Publication Date: 2020-12-08
- Inventor: Kevin J. Tracey , Huan Yang , Yousef Al-Abed
- Applicant: The Feinstein Institue for Medical Research
- Applicant Address: US NY Manhasset
- Assignee: THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH
- Current Assignee: THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH
- Current Assignee Address: US NY Manhasset
- Agency: Tarolli, Sundheim, Covell & Tummino LLP
- International Application: PCT/US2015/065521 WO 20151214
- International Announcement: WO2016/094899 WO 20160616
- Main IPC: A61K38/07
- IPC: A61K38/07 ; A61K38/04 ; C07K5/00 ; A61P29/00 ; A61K31/7024 ; A61K31/215 ; C07K5/107
Abstract:
Methods of treating HMGB1-mediated inflammation by administering a therapeutically effective amount of an MD2-antagonist to a subject in need thereof are described. The novel MD2 antagonist tetrapeptide P5779 is also described.
Public/Granted literature
- US20180353564A1 TREATMENT OF HMGB1-MEDIATED INFLAMMATION Public/Granted day:2018-12-13
Information query
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