Invention Grant
- Patent Title: Bicyclic imidazole derivatives useful for the treatment of renal diseases, cardiovascular diseases and fibrotic diseases
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Application No.: US16310458Application Date: 2017-06-21
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Publication No.: US10858342B2Publication Date: 2020-12-08
- Inventor: Michael Balestra , Jennifer Burke , Zhidong Chen , Derek Cogan , John Lord , Daniel Richard Marshall , Bryan P. McKibben , Kenneth M. Meyers , Yunlong Zhang
- Applicant: Boehringer Ingelheim International GmbH
- Applicant Address: DE Ingelheim am Rhein
- Assignee: Boehringer Ingelheim International GmbH
- Current Assignee: Boehringer Ingelheim International GmbH
- Current Assignee Address: DE Ingelheim am Rhein
- Agent David L. Kershner
- International Application: PCT/US2017/038440 WO 20170621
- International Announcement: WO2018/005177 WO 20180104
- Main IPC: C07D403/04
- IPC: C07D403/04 ; C07D235/26 ; C07D401/04 ; C07D403/06 ; C07D403/10 ; C07D405/04 ; C07D405/06 ; C07D413/04 ; C07D417/06 ; C07D471/04 ; C07D491/107 ; C07D498/04
Abstract:
The present invention relates to compounds of formula I: and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, R5 and n are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.
Public/Granted literature
Information query
