The present disclosure provides a display panel, a manufacturing method thereof and a display device. The display panel includes an opposite substrate and a display substrate opposite each other, a sealant is disposed between the opposite substrate and the display substrate, and the display substrate may be divided into a display area and a peripheral area around the display area. The display substrate includes a first base substrate; a first resin pattern on the first base substrate in the display area; and a protection layer in the display area and the peripheral area and between the first resin pattern and the first base substrate. The sealant is in the peripheral area and in contact with a portion of the protection layer in the peripheral area.