The present application relates to a method for acquiring maximum principal strain or a maximum principal stress status of a vessel wall. The method includes: acquiring first vessel data of a first time phase corresponding to a vessel; acquiring second vessel data of a second time phase corresponding to the vessel; generating, based on the first vessel data, a first vessel model relating to the first time phase, generating a second vessel model relating to the second time phase based on the second vessel data; determining a region of interest in the first vessel model; determining the corresponding region of interest in the second vessel model; determining a reference point in the region of interest of the first vessel model; determining the corresponding reference point in the region of interest of the second vessel model; determining a displacement of the reference point from the first vessel model to the second vessel model; and determining a maximum principal strain or a maximum principal stress at the reference point based on the displacement of the reference point.