The present invention relates to a multi-banknote cassette with a movable stopper, and more particularly, to a multi-banknote cassette with a movable stopper, which is capable of storing various kinds of banknotes at the same time. The multi-banknote cassette may include: a stopper driver which is formed at the top of a cassette body and has a pinion gear rotated by a driving motor; and a movable stopper which has a rack gear formed at one side surface thereof and engaged with the pinion gear and is lifted/lowered vertically through a stack guide to guide an introduced banknote in the cassette body, while the pinion gear of the stopper driver is rotated. Through such a structure, various kinds of banknotes can be easily handled in one banknote cassette.