A method of manufacturing an imaging system includes selecting a golden sample camera module, an upper sample camera module, and a lower sample camera module from a population of camera modules; measuring a golden sample non-uniformity profile at a plurality of CCTs for the golden sample camera module; measuring an upper sample non-uniformity profile at the plurality of CCTs for the upper sample camera module; measuring a lower sample non-uniformity profile at the plurality of CCTs for the lower sample camera module; calculating an anchor non-uniformity profile at each CCT for the population of camera modules by a weighted average of the golden sample non-uniformity profile, the upper sample non-uniformity profile, and the lower sample non-uniformity profile at each CCT; and storing a plurality of anchor non-uniformity profiles in a hardware storage device of the imaging system including a first camera module of the population of camera modules.