Invention Grant
- Patent Title: Tricyclic compounds and their use in the treatment of cancer
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Application No.: US15750819Application Date: 2016-08-05
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Publication No.: US10881653B2Publication Date: 2021-01-05
- Inventor: Elias Set Jenö Arnér , William Chester Stafford , Nathan Patrick Coussens , Diane Karen Luci , David Joseph Maloney , Anton Simeonov , Ajit Jadhav , Thomas S. Dexheimer
- Applicant: Elias Set Jenö Arnér , The United States of America, as represented by the Secretary, Department of Health and Human Services
- Applicant Address: SE Stockholm; US MD Bethesda
- Assignee: Elias Set Jenö Arnér,The United States of America, as represented by the Secretary, Department of Health and Human Services
- Current Assignee: Elias Set Jenö Arnér,The United States of America, as represented by the Secretary, Department of Health and Human Services
- Current Assignee Address: SE Stockholm; US MD Bethesda
- Agency: McCarter & English, LLP
- Agent Steven G. Davis; Mei Bai
- Priority: GB1514018.9 20150807
- International Application: PCT/US2016/045730 WO 20160805
- International Announcement: WO2017/027358 WO 20170216
- Main IPC: A61K31/46
- IPC: A61K31/46 ; A61P35/00 ; C07D451/00

Abstract:
There is provided compounds of formula (I), or pharmaceutically-acceptable salts thereof, wherein X, Y, Z, R1 and R2 have meanings provided in the description, which compounds are useful in the treatment of cancers.
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