Invention Grant
- Patent Title: Cholestyramine granules, oral cholestyramine formulations and use thereof
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Application No.: US16125358Application Date: 2018-09-07
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Publication No.: US10881685B2Publication Date: 2021-01-05
- Inventor: Per-Göran Gillberg , Nils Ove Gustafsson , Kurt Lövgren
- Applicant: Albireo AB
- Applicant Address: SE Gothenburg
- Assignee: Albireo AB
- Current Assignee: Albireo AB
- Current Assignee Address: SE Gothenburg
- Agency: Fish & Richardson P.C.
- Priority: SE1750978 20170809
- Main IPC: A61K31/785
- IPC: A61K31/785 ; A61K9/16 ; A61P1/12 ; A61K9/50 ; A61P1/00
Abstract:
The invention relates to small granules comprising cholestyramine. The granules have a high cholestyramine content and are stable enough to be coated with one or more coating layers. The invention also relates to a multiparticulate drug delivery system comprising such granules. The invention further relates to an oral formulation for targeted delivery of cholestyramine to the colon, comprising a plurality of cholestyramine granules that are coated with a colon release coating. The invention also relates to the use of this formulation in the treatment of bile acid malabsorption and bile acid diarrhoea.
Public/Granted literature
- US20190070217A1 CHOLESTYRAMINE GRANULES, ORAL CHOLESTYRAMINE FORMULATIONS AND USE THEREOF Public/Granted day:2019-03-07
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