Invention Grant
- Patent Title: Hepatitis C virus immunogenic compositions and methods of use thereof
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Application No.: US16336732Application Date: 2017-10-05
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Publication No.: US10881726B2Publication Date: 2021-01-05
- Inventor: Michael Houghton , Abdolamir Landi , Carlos A. Guzman , Thomas Ebensen , Darren Hockman , John L. Law , Michael Logan
- Applicant: The Governors of the University of Alberta , Helmholtz Center for Infection Research
- Applicant Address: CA Edmonton; DE Braunschweig
- Assignee: The Governors of the University of Alberta,Helmholtz Center for Infection Research
- Current Assignee: The Governors of the University of Alberta,Helmholtz Center for Infection Research
- Current Assignee Address: CA Edmonton; DE Braunschweig
- Agency: Bozicevic Field & Francis, LLP
- Agent Paula A. Borden
- International Application: PCT/CA2017/051192 WO 20171005
- International Announcement: WO2018/068132 WO 20180419
- Main IPC: A61K39/00
- IPC: A61K39/00 ; A61K39/12 ; A61K39/39 ; A61K31/675 ; A61K39/095 ; A61K39/29 ; A61P31/14 ; A61P37/04 ; C07K14/005 ; C01F11/02 ; C07D323/00 ; C07K14/18 ; C07K14/28 ; C07K14/33 ; C07K14/34 ; C12N15/86
Abstract:
The present disclosure provides immunogenic compositions comprising: a) hepatitis C virus (HCV) E1E2 heterodimers, HCV E2, or HCV E1; and b) an adjuvant, where the adjuvant is a cyclic dinucleotide or an archaeosome. The present disclosure provides methods of inducing an immune response in an individual to HCV, the methods comprising administering to an individual an effective amount of an immunogenic composition of the present disclosure.
Public/Granted literature
- US20190231867A1 HEPATITIS C VIRUS IMMUNOGENIC COMPOSITIONS AND METHODS OF USE THEREOF Public/Granted day:2019-08-01
Information query
