Invention Grant
- Patent Title: Sentinel lymph node marker capable of multi-mode imaging
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Application No.: US13816931Application Date: 2011-08-16
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Publication No.: US10881750B2Publication Date: 2021-01-05
- Inventor: Seok Ki Kim , Se Hun Kang , Seo Il Kim , Young Sang Kim , Nam Suk Baek , Jin Hee Noh
- Applicant: Seok Ki Kim , Se Hun Kang , Seo Il Kim , Young Sang Kim , Nam Suk Baek , Jin Hee Noh
- Applicant Address: KR Goyang-si; KR Goyang-si; KR Goyang-si; KR Goyang-si; KR Goyang-si; KR Goyang-si
- Assignee: Seok Ki Kim,Se Hun Kang,Seo Il Kim,Young Sang Kim,Nam Suk Baek,Jin Hee Noh
- Current Assignee: Seok Ki Kim,Se Hun Kang,Seo Il Kim,Young Sang Kim,Nam Suk Baek,Jin Hee Noh
- Current Assignee Address: KR Goyang-si; KR Goyang-si; KR Goyang-si; KR Goyang-si; KR Goyang-si; KR Goyang-si
- Agency: Sughrue Mion, PLLC
- Priority: KR10-2010-0078330 20100813
- International Application: PCT/KR2011/005994 WO 20110816
- International Announcement: WO2012/021045 WO 20120216
- Main IPC: A61K51/08
- IPC: A61K51/08 ; A61K49/00 ; G01N33/534

Abstract:
The present invention relates to a sentinel lymph node marker comprising an albumin; a radioactive isotope and/or near infrared dye which is bound to the albumin; and a visible dye which is bound to the albumin, a preparation method thereof, and a kit for multimode imaging of a sentinel lymph node to prepare the sentinel lymph node marker. The sentinel lymph node marker of the invention remains in the sentinel lymph node for a long period of time and allows for multimode imaging of the sentinel lymph node. Thus, using this marker the sentinel lymph node can be accurately identified in vivo by near infrared imaging and/or gamma imaging without incision of skin, and the location of the identified sentinel lymph node can be precisely identified with the naked eye during a surgical operation of removing the identified sentinel lymph node.
Public/Granted literature
- US20130309169A1 Sentinel Lymph Node Marker Capable of Multi-Mode Imaging Public/Granted day:2013-11-21
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