Invention Grant
- Patent Title: Transcriptome transfer produces cellular phenotype conversion
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Application No.: US14230848Application Date: 2014-03-31
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Publication No.: US10883082B2Publication Date: 2021-01-05
- Inventor: James Eberwine , Jai-Yoon Sul , Chia-Wen Wu , Fanyi Zeng , Junhyong Kim
- Applicant: The Trustees of the University of Pennsylvania
- Applicant Address: US PA Philadelphia
- Assignee: The Trustees of the University of Pennsylvania
- Current Assignee: The Trustees of the University of Pennsylvania
- Current Assignee Address: US PA Philadelphia
- Agency: Riverside Law LLP
- Main IPC: C12N5/0793
- IPC: C12N5/0793 ; C12N5/079 ; C12N5/077 ; C12N15/85 ; C12N15/87

Abstract:
The present invention includes methods for effecting phenotype conversion in a cell by transfecting the cell with phenotype-converting nucleic acid. Expression of the nucleic acids results in a phenotype conversion in the transfected cell. Preferably the phenotype-converting nucleic acid is a transcriptome, and more preferably an mRNA transcriptome.
Public/Granted literature
- US20140206059A1 Transcriptome Transfer Produces Cellular Phenotype Conversion Public/Granted day:2014-07-24
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