• Patent Title: Peptides of M. tuberculosis for a screening test for HIV positive patients at high-risk for tuberculosis
  • Application No.: US15564086
    Application Date: 2016-04-04
  • Publication No.: US10883989B2
    Publication Date: 2021-01-05
  • Inventor: Suman Laal
  • Applicant: New York University
  • Applicant Address: US NY New York
  • Assignee: New York University
  • Current Assignee: New York University
  • Current Assignee Address: US NY New York
  • Agency: Hodgson Russ LLP
  • International Application: PCT/US2016/025894 WO 20160404
  • International Announcement: WO2016/161435 WO 20161006
  • Main IPC: G01N33/569
  • IPC: G01N33/569
Peptides of M. tuberculosis for a screening test for HIV positive patients at high-risk for tuberculosis
Abstract:
Provided are peptides suitable for early detection of active M. tuberculosis (Mtb) infection in immunocompromised individuals. The peptides can form complexes with antibodies directed to Mtb antigens MS, MPT51, ESAT6 or CFPIO. Also provided are methods for detected of complexes of the peptides and the antibodies. The presence of complexes aids in predicting risk in immunocompromised individuals of developing active tuberculosis.
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