An audio control system can automatically determine an occupancy of an audience seating area, and can automatically adjust a spectral content of an audio signal to at least partially compensate for spectral effects caused by the occupancy in the audience seating area. Such an audio control system can ensure that the sound in a particular room remains constant, or nearly constant, from performance to performance. The occupancy can include a number of people in attendance in the audience seating area, and/or locations of attendees in the audience seating area. The audio control system can automatically adjust the spectral content a single time, at the start of a performance, or can optionally automatically dynamically update the adjustment throughout the performance based on subsequent measurements of the occupancy. The system can determine the occupancy through ticket sales, and/or analysis of imaging of the seats in the audience seating area.