Invention Grant
- Patent Title: Biemamides and related scaffolds as inhibitors of transforming growth factor-beta signaling
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Application No.: US16551534Application Date: 2019-08-26
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Publication No.: US10889551B2Publication Date: 2021-01-12
- Inventor: Timothy Bugni , Fan Zhang , Douglas Braun , Gene Ananiev , F. Michael Hoffmann
- Applicant: Wisconsin Alumni Research Foundation
- Applicant Address: US WI Madison
- Assignee: Wisconsin Alumni Research Foundation
- Current Assignee: Wisconsin Alumni Research Foundation
- Current Assignee Address: US WI Madison
- Agency: Foley & Lardner LLP
- Main IPC: C07D239/22
- IPC: C07D239/22
Abstract:
The present technology provides an isolated compound of Formula I, compositions including such compounds, methods of inhibiting TGF-β signaling and/or TGF-β induced epithelial mesenchymal transitions (EMT), and treating certain cancers involving TGF-β signaling and/or EMT.
Public/Granted literature
- US20200062715A1 BIEMAMIDES AND RELATED SCAFFOLDS AS INHIBITORS OF TRANSFORMING GROWTH FACTOR-BETA SIGNALING Public/Granted day:2020-02-27
Information query
