Invention Grant
- Patent Title: Compositions and methods for treating conditions related to ephrin signaling with Cupredoxins
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Application No.: US15963605Application Date: 2018-04-26
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Publication No.: US10889621B2Publication Date: 2021-01-12
- Inventor: Ananda Chakrabarty , Tapas Das Gupta , Tohru Yamada , Anita Chaudhari , Arsenio Fialho , Yonghua Zhu
- Applicant: The Board of Trustees of the University of Illinois
- Applicant Address: US IL Urbana
- Assignee: The Board of Trustees of the University of Illinois
- Current Assignee: The Board of Trustees of the University of Illinois
- Current Assignee Address: US IL Urbana
- Agency: Benesch, Friedlander, Coplan & Aronoff LLP
- Main IPC: C07K14/21
- IPC: C07K14/21 ; A61K38/16 ; C07K14/195 ; C07K14/705

Abstract:
The present invention relates to compositions and methods of use of cupredoxins, and variants, derivatives and structural equivalents of cupredoxins that interfere with the ephrin signaling system in mammalian cells. Specifically, the invention relates to compositions and methods that use cupredoxins, such as azurin, rusticyanin and plastocyanin, and variants, derivatives and structural equivalents thereof, to treat cancer in mammals.
Public/Granted literature
- US20180319847A1 COMPOSITIONS AND METHODS FOR TREATING CONDITIONS RELATED TO EPHRIN SIGNALING WITH CUPREDOXINS Public/Granted day:2018-11-08
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