A disclosed example to configure an application blueprint includes binding, during a design phase, a service template to a node of the application blueprint, the application blueprint corresponding to an application to be deployed, the service template mapped to a plurality of services to be selectable during a runtime phase to implement the node; and storing, during the design phase, the application blueprint for subsequent access during the runtime phase to generate a first deployment profile and a second deployment profile, the first deployment profile to deploy a first instance of the application based on a first service selected from the service template to implement the node, and the second deployment profile to deploy a second instance of the application based on a second service, different from the first service, selected from the service template to implement the node.