A method and a transmitter arrangement for cancelling cross talk and correcting power amplifier (PA) distortion for a transmitter branch of a multiple-input multiple-output (MIMO) configuration having multiple branches. The method comprises combining an original baseband input signal of a first MIMO transmitter branch with a crosstalk output signal generated from two or more signals associated with two or more respective MIMO branches, the two or more signals used as input to, and processed by, a crosstalk model. The method further comprises processing the combined signal to generate an output signal in order to minimize the error of the original baseband input signal caused by the crosstalk and/or PA distortion.