Systems, devices, and associated methods of manufacturing are described that provide a rodent extermination system for efficient rodent population control. An example rodent extermination system includes a vacuum unit configured to generate suction and an extermination chamber. The extermination chamber defines a first end attached to and in fluid communication with the vacuum unit and a second end in fluid communication with an external environment. The system also includes at least one presence sensor and at least two electrocution plates. The at least two electrocution plates are electrified such that the rodent is electrocuted via contact with the electrocution plates, and the vacuum unit generates suction such that the rodent is moved through the extermination chamber. The vacuum unit may comprise a kill plate into which the rodent is ejected at high velocity in order to induce cervical dislocation or blunt force trauma to the rodent.