Invention Grant
- Patent Title: Combination of topoisomerase-I inhibitors with immunotherapy in the treatment of cancer
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Application No.: US15760995Application Date: 2016-09-16
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Publication No.: US10894044B2Publication Date: 2021-01-19
- Inventor: Patrick Hwu , Jodi A. McKenzie , Rina M. Mbofung , Rodabe Amaria
- Applicant: Board of Regents, The University of Texas System
- Applicant Address: US TX Austin
- Assignee: Board of Regents, The University of Texas System
- Current Assignee: Board of Regents, The University of Texas System
- Current Assignee Address: US TX Austin
- Agent Dennis A. Bennett; Cynthia Hathaway; John Deeper
- International Application: PCT/US2016/052303 WO 20160916
- International Announcement: WO2017/049199 WO 20170323
- Main IPC: A61K31/4745
- IPC: A61K31/4745 ; A61K9/00 ; A61K39/395 ; C07K16/28 ; A61K9/127 ; A61P35/00 ; A61K39/00

Abstract:
The present disclosure relates to compositions and methods for treating cancer, more specifically to methods and compositions comprising a Topoisomerase I inhibitor and an α-PD-L1 antibody.
Public/Granted literature
- US20180263971A1 COMBINATION OF TOPOISOMERASE-I INHIBITORS WITH IMMUNOTHERAPY IN THE TREATMENT OF CANCER Public/Granted day:2018-09-20
Information query
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