Invention Grant
- Patent Title: Salt of (R)-(1-methylpyrrolidine-3-yl)methyl(3′-chloro-4′-fluoro-[1,1′-biphenyl]-2-yl)carbamate and crystal form thereof
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Application No.: US16328492Application Date: 2016-08-26
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Publication No.: US10894768B2Publication Date: 2021-01-19
- Inventor: Woo Young Kwak , Chang-Yong Shin , Punna Reddy Ullapu , Sun-Ho Choi , Min-Jung Lee , Ji-Su Kim
- Applicant: Dong-A St Co., Ltd.
- Applicant Address: KR Seoul
- Assignee: Dong-A St Co., Ltd.
- Current Assignee: Dong-A St Co., Ltd.
- Current Assignee Address: KR Seoul
- Agency: Fish & Richardson P.C.
- International Application: PCT/KR2016/009558 WO 20160826
- International Announcement: WO2018/038297 WO 20180301
- Main IPC: C07D207/09
- IPC: C07D207/09 ; A61K31/40 ; C07D207/08
![Salt of (R)-(1-methylpyrrolidine-3-yl)methyl(3′-chloro-4′-fluoro-[1,1′-biphenyl]-2-yl)carbamate and crystal form thereof](/abs-image/US/2021/01/19/US10894768B2/abs.jpg.150x150.jpg)
Abstract:
The present invention relates to a novel salt of (R)-(1-methylpyrrolidine-3-yl)methyl(3′-chloro-4′-fluoro-[1,1′-biphenyl]-2-yl)carbamate and a crystal form thereof. Also, the novel salt of (R)-(1-methylpyrrolidine-3-yl)methyl(3′-chloro-4′-fluoro-[1,1′-biphenyl]-2-yl)carbamate and the crystal form thereof according to examples of the present invention have remarkably excellent stability, hygroscopicity and solubility.
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