- Patent Title: Substituted pyrazole derivatives as selective CDK12/13 inhibitors
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Application No.: US16374842Application Date: 2019-04-04
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Publication No.: US10894786B2Publication Date: 2021-01-19
- Inventor: Ramulu Poddutoori , Susanta Samajdar , Subhendu Mukherjee
- Applicant: Aurigene Discovery Technologies Limited
- Applicant Address: IN Bangalore
- Assignee: Aurigene Discovery Technologies Limited
- Current Assignee: Aurigene Discovery Technologies Limited
- Current Assignee Address: IN Bangalore
- Agent Benjamin Aaron Adler
- Priority: IN201841012850 20180404
- Main IPC: A61K31/4439
- IPC: A61K31/4439 ; C07D401/12 ; C07D401/14 ; A61P35/00 ; C07D403/12 ; C07D413/14 ; C07D231/40
Abstract:
The present invention provides substituted pyrazole derivatives of formula (I) which are therapeutically useful as selective CDK12/13 inhibitors. These compounds are useful in the treatment and/or prevention of diseases and/or disorders associated with CDK12/13 in a mammal. The present invention also provides preparation of the compounds and pharmaceutical compositions with at least one of the substituted pyrazole derivatives of formula (I) or a pharmaceutically acceptable salt, an N-oxide or a stereoisomer thereof.
Public/Granted literature
- US20200308142A9 Substituted Pyrazole Derivatives As Selective CDK12/13 Inhibitors Public/Granted day:2020-10-01
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