Invention Grant
- Patent Title: Peptide inhibitors of calcium channels
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Application No.: US16078397Application Date: 2017-02-22
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Publication No.: US10894811B2Publication Date: 2021-01-19
- Inventor: Robert Tarran , Tongde Wu
- Applicant: The University of North Carolina at Chapel Hill
- Applicant Address: US NC Chapel Hill
- Assignee: The University of North Carolina at Chapel Hill
- Current Assignee: The University of North Carolina at Chapel Hill
- Current Assignee Address: US NC Chapel Hill
- Agency: Myers Bigel, P.A.
- International Application: PCT/US2017/018840 WO 20170222
- International Announcement: WO2017/147128 WO 20170831
- Main IPC: C07K14/47
- IPC: C07K14/47 ; C07K14/435 ; A61P37/08 ; A61P37/06 ; A61K38/00 ; A61K9/00
Abstract:
The present invention relates to fragments of SPLUNC1 protein that bind to calcium channels and inhibit calcium influx into airway smooth muscle and other cells. The invention further relates to methods for regulating calcium influx and treating or preventing disorders responsive to modulating calcium influx through calcium channels.
Public/Granted literature
- US20190062386A1 PEPTIDE INHIBITORS OF CALCIUM CHANNELS Public/Granted day:2019-02-28
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