Invention Grant
- Patent Title: Agents, uses and methods for treatment
-
Application No.: US16037790Application Date: 2018-07-17
-
Publication No.: US10894833B2Publication Date: 2021-01-19
- Inventor: Lars Christian Biilmann Rønn , Ibrahim John Malik , Jeffrey B. Stavenhagen , Søren Christensen , Jan Egebjerg , Tina Stummann , Arnout Gerritsen , Edward van den Brink , Paul Parren
- Applicant: H. Lundbeck A/S
- Applicant Address: DK Valby
- Assignee: H. Lundbeck A/S
- Current Assignee: H. Lundbeck A/S
- Current Assignee Address: DK Valby
- Agency: Wolf, Greenfield & Sacks, P.C.
- Priority: DK201700419 20170720
- Main IPC: C07K16/28
- IPC: C07K16/28 ; A61K39/00

Abstract:
The present invention relates to monoclonal anti-Sortilin antibodies which have been found useful in correcting a deficient level of progranulin (PGRN). In particular, these antibodies can be used in the treatment of frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS) and other neurodegenerative disorders such as Alzheimers disease (AD).
Public/Granted literature
- US20190023788A1 AGENTS, USES AND METHODS FOR TREATMENT Public/Granted day:2019-01-24
Information query