Invention Grant
- Patent Title: Spherical nucleic acid-based constructs as immunostimulatory agents for prophylactic and therapeutic use
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Application No.: US14907430Application Date: 2014-07-25
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Publication No.: US10894963B2Publication Date: 2021-01-19
- Inventor: Aleksandar Filip Radovic-Moreno , Christopher C. Mader , Subbarao Nallagatla , Warefta Hasan , Aaron Love , Sergei Gryaznov
- Applicant: Exicure, Inc.
- Applicant Address: US IL Chicago
- Assignee: Exicure, Inc.
- Current Assignee: Exicure, Inc.
- Current Assignee Address: US IL Chicago
- Agency: Wolf, Greenfield & Sacks, P.C.
- International Application: PCT/US2014/048291 WO 20140725
- International Announcement: WO2015/013673 WO 20150129
- Main IPC: C12N15/117
- IPC: C12N15/117 ; A61K39/39 ; B82Y5/00 ; A61K39/00
Abstract:
Aspects of the invention relate to spherical nucleic acid-based constructs and related methods and compositions thereof. The compositions of the invention are useful for activating agonists of nucleic acid interacting complexes, such as TLRs, stimulating an immune response, and treating diseases such as infectious disease, cancer, allergies, allergic diseases, and autoimmune disease
Public/Granted literature
- US20160186178A1 SPHERICAL NUCLEIC ACID-BASED CONSTRUCTS AS IMMUNOSTIMULATORY AGENTS FOR PROPHYLACTIC AND THERAPEUTIC USE Public/Granted day:2016-06-30
Information query
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