Invention Grant
- Patent Title: Macrophage migration inhibitory factor inhibitors, and methods of making and using same
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Application No.: US16186974Application Date: 2018-11-12
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Publication No.: US10899739B2Publication Date: 2021-01-26
- Inventor: William L. Jorgensen
- Applicant: YALE UNIVERSITY
- Applicant Address: US CT New Haven
- Assignee: YALE UNIVERSITY
- Current Assignee: YALE UNIVERSITY
- Current Assignee Address: US CT New Haven
- Agency: Saul Ewing Arnstein & Lehr LLP
- Agent Kathryn Doyle; Domingos J. Silva
- Main IPC: C07D401/14
- IPC: C07D401/14 ; A61P37/06 ; C07D249/04 ; C07C13/16 ; A61P35/00 ; C07D401/04
Abstract:
The present invention provides novel inhibitors of MIF tautomerase activity. In certain embodiments, the compounds of the invention are useful in treating or preventing inflammatory and/or auto-immune diseases. In other embodiments, the compounds of the invention are useful in reversing, ameliorating, and/or preventing tumor growth. In yet other embodiments, the compounds of the invention are useful in reversing, ameliorating, and/or preventing angiogenesis.
Public/Granted literature
- US20190144424A1 Macrophage Migration Inhibitory Factor Inhibitors, and Methods of Making and Using Same Public/Granted day:2019-05-16
Information query
