Invention Grant
- Patent Title: Compositions and methods for inhibiting arginase activity
-
Application No.: US16525403Application Date: 2019-07-29
-
Publication No.: US10905701B2Publication Date: 2021-02-02
- Inventor: Matthew I. Gross , Susanne M. Steggerda , Weiqun Li
- Applicant: CALITHERA BIOSCIENCES, INC.
- Applicant Address: US CA South San Francisco
- Assignee: CALITHERA BIOSCIENCES, INC.
- Current Assignee: CALITHERA BIOSCIENCES, INC.
- Current Assignee Address: US CA South San Francisco
- Agency: Dechert LLP
- Agent Carl A. Morales; Seth E. Snyder
- Main IPC: A61K31/69
- IPC: A61K31/69 ; A61K39/00 ; A61K45/06 ; C07K16/28 ; G01N33/50 ; A61K39/395

Abstract:
The invention relates to methods of treating cancer, with a combination of an arginase inhibitor and a chemotherapeutic agent. The invention further relates to methods of assessing efficacy of a cancer treatment by measuring arginine levels in a tumor.
Information query