Invention Grant
- Patent Title: Treatment of gastrointestinal bleeding in patients with severe von Willebrand disease by administration of recombinant VWF
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Application No.: US16802118Application Date: 2020-02-26
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Publication No.: US10905746B2Publication Date: 2021-02-02
- Inventor: Miranda Chapman , Bruce Ewenstein , Bettina Ploder
- Applicant: Baxalta Incorporated , Baxalta GmbH
- Applicant Address: US IL Bannockburn; CH Glattpark
- Assignee: Baxalta Incorporated,Baxalta GmbH
- Current Assignee: Baxalta Incorporated,Baxalta GmbH
- Current Assignee Address: US IL Bannockburn; CH Glattpark
- Agency: Morgan, Lewis & Bockius LLP
- Main IPC: A61K38/00
- IPC: A61K38/00 ; A61K38/37 ; A61K38/36 ; A61P7/04
Abstract:
The present invention relates to a method for treating gastrointestinal bleeding in a subject with severe von Willebrand Disease comprising administering to the subject at least one dose of recombinant von Willebrand Factor (rVWF) ranging from about 40 IU/kg to about 100 IU/kg, wherein the first dose further comprises recombinant Factor VIII (rFVIII).
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