A honeycomb structural body includes: a porous cell wall that partitions a cylindrical casing; and a large number of cells extending in the axial direction X thereof and alternately blocked at an upstream end face. The large number of cells include plugged cells having plugs and penetrating cells that do not have the plugs. The plugged cells and the penetrating cells both include complete cells and incomplete cells. At least some of plugged incomplete cells of the incomplete cells have a cross-sectional area smaller than a cross-sectional area of penetrating complete cells, and are configured as blocked cells that are entirely blocked inside in the axial direction.