Invention Grant
- Patent Title: Kinase inhibitors for the treatment of disease
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Application No.: US16403793Application Date: 2019-05-06
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Publication No.: US10906878B2Publication Date: 2021-02-02
- Inventor: Nathanael S. Gray , Hwan G. Choi , Li Tan
- Applicant: Dana-Farber Cancer Institute, Inc.
- Applicant Address: US MA Boston
- Assignee: Dana-Farber Cancer Institute, Inc.
- Current Assignee: Dana-Farber Cancer Institute, Inc.
- Current Assignee Address: US MA Boston
- Agency: Burns & Levinson, LLP
- Agent Daniel W. Clarke
- Main IPC: C07D239/48
- IPC: C07D239/48 ; C07D487/04 ; C07D401/12 ; A61K31/5377 ; A61K31/519 ; A61K31/517 ; A61K31/506 ; A61K31/505 ; A61K45/06 ; C07D409/14 ; C07D471/04 ; C07D409/12 ; C07D405/12 ; C07D405/14 ; C07D403/12
Abstract:
The invention relates to compounds and their use in the treatment of disease. Novel irreversible inhibitors of wild-type and mutant forms of EGFR, FGFR, ALK, ROS, JAK, BTK, BLK, ITK, TEC, and/or TXK and their use for the treatment of cell proliferation disorders are described.
Public/Granted literature
- US20190256475A1 KINASE INHIBITORS FOR THE TREATMENT OF DISEASE Public/Granted day:2019-08-22
Information query
