Invention Grant
![Substituted 5,6,7,8-tetrahydroimidazo[1,5-a]pyrazines as factor xia inhibitors](/docs/US/2021-02-02/US10906886B2/abs.jpg.600x600.jpg)
- Patent Title: Substituted 5,6,7,8-tetrahydroimidazo[1,5-a]pyrazines as factor xia inhibitors
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Application No.: US15982038Application Date: 2018-05-17
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Publication No.: US10906886B2Publication Date: 2021-02-02
- Inventor: Donald J. P. Pinto , Indawati De Lucca
- Applicant: BRISTOL-MYERS SQUIBB COMPANY
- Applicant Address: US NJ Princeton
- Assignee: BRISTOL-MYERS SQUIBB COMPANY
- Current Assignee: BRISTOL-MYERS SQUIBB COMPANY
- Current Assignee Address: US NJ Princeton
- Agency: Mintz, Levin, Cohn, Ferris, Glovsky and Popeo, P.C.
- Main IPC: A61K31/4985
- IPC: A61K31/4985 ; C07D487/04 ; C07D401/10 ; C07D401/14 ; C07D413/14 ; C07D217/26 ; C07D471/04 ; C07D401/12
![Substituted 5,6,7,8-tetrahydroimidazo[1,5-a]pyrazines as factor xia inhibitors](/abs-image/US/2021/02/02/US10906886B2/abs.jpg.150x150.jpg)
Abstract:
The present invention provides compounds of Formula (I): or stereoisomers, pharmaceutically acceptable salts thereof, wherein all of the variables are as defined herein. These compounds are inhibitors of factor XIa andor plasma kallikrein which may be used as medicaments.
Public/Granted literature
- US20180265494A1 SUBSTITUTED TETRAHYDROISOQUINOLINE COMPOUNDS AS FACTOR XIA INHIBITORS Public/Granted day:2018-09-20
Information query
IPC分类:
