Invention Grant
- Patent Title: Method for purifying antibodies
-
Application No.: US14995278Application Date: 2016-01-14
-
Publication No.: US10906935B2Publication Date: 2021-02-02
- Inventor: David Meh , Timothy Atolagbe , G. Mark Farquharson , Samir Shaban , Mary Koleck , George Mitra
- Applicant: United Therapeutics Corporation , The United States of America as represented by the Secretary, Department of Health and Human Services
- Applicant Address: US MD Silver Spring; US MD Bethesda
- Assignee: United Therapeutics Corporation,The United States of America as represented by the Secretary, Department of Health and Human Services
- Current Assignee: United Therapeutics Corporation,The United States of America as represented by the Secretary, Department of Health and Human Services
- Current Assignee Address: US MD Silver Spring; US MD Bethesda
- Agency: Foley & Lardner LLP
- Main IPC: C07K1/36
- IPC: C07K1/36 ; C07K1/18 ; B01D15/36 ; C07K1/34 ; C07K1/14 ; C07K16/30 ; C07K16/18 ; B01D15/12 ; B01D15/18 ; B01D15/24 ; B01D15/38 ; B01D61/14 ; B01D61/16

Abstract:
Disclosed here includes a method for purifying a biologic composition, comprising diafiltering the biologic composition into a composition comprising phosphate buffered saline (PBS) to obtain a purified composition. The method disclosed here can be particularly useful for removing one or more impurities from the biologic composition, such as bis(2-hydroxyethyl)amino-tris(hydroxymethyl)methane (Bis-tris).
Public/Granted literature
- US20160289268A1 METHOD FOR PURIFYING ANTIBODIES Public/Granted day:2016-10-06
Information query