Invention Grant
- Patent Title: Virus-like particles with high-density coating for inducing the expression of antibodies
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Application No.: US16321271Application Date: 2017-07-26
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Publication No.: US10906943B2Publication Date: 2021-02-02
- Inventor: Jorge Carrillo Molina , Luis M. Molinos-Albert , Julián Miguel Blanco Arbués
- Applicant: FUNDACIO PRIVADA INSTITUT DE RECERCA DE LA SIDA-CAIXA
- Applicant Address: ES Barcelona
- Assignee: FUNDACIO PRIVADA INSTITUT DE RECERCA DE LA SIDA-CAIXA
- Current Assignee: FUNDACIO PRIVADA INSTITUT DE RECERCA DE LA SIDA-CAIXA
- Current Assignee Address: ES Barcelona
- Agent Gary J. Gershik
- Priority: EP16382364 20160727
- International Application: PCT/IB2017/001101 WO 20170726
- International Announcement: WO2018/020324 WO 20180201
- Main IPC: A61K39/00
- IPC: A61K39/00 ; A61K39/12 ; C12N7/00 ; C07K14/005 ; A61K39/145 ; A61P31/18 ; A61K39/21 ; C07K14/705
Abstract:
The invention relates to a fusion protein comprising a polypeptide of interest, a transmembrane domain and an HIV gag polypeptide, or their functionally equivalent variants. The invention also relates to the polynucleotides, vectors, host cells and virus-like particles expressing or presenting said fusion proteins and to the pharmaceutical, immunogenic or vaccines composition containing said fusion proteins, polynucleotides, vectors, host cells and virus-like particles and their use in human and veterinary medicine.
Public/Granted literature
- US20190315807A1 VIRUS-LIKE PARTICLES WITH HIGH-DENSITY COATING FOR INDUCING THE EXPRESSION OF ANTIBODIES Public/Granted day:2019-10-17
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