Invention Grant
- Patent Title: Modified alpha hemolysin polypeptides and methods of use
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Application No.: US16034115Application Date: 2018-07-12
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Publication No.: US10906945B2Publication Date: 2021-02-02
- Inventor: Geoffrey A. Barrall , Eric N. Ervin , Prithwish Pal
- Applicant: ELECTRONIC BIOSCIENCES, INC.
- Applicant Address: US CA San Diego
- Assignee: ELECTRONIC BIOSCIENCES, INC.
- Current Assignee: ELECTRONIC BIOSCIENCES, INC.
- Current Assignee Address: US CA San Diego
- Agency: Grant IP, Inc.
- Main IPC: C07K14/31
- IPC: C07K14/31 ; C12Q1/6869
Abstract:
Provided herein are alpha hemolysin polypeptides comprising modified amino acid sequences that can reduce the rate of translocation of a polymer. Also provided herein are apparatuses and devices comprising modified hemolysin polypeptides. Also provided herein are methods of using modified alpha hemolysin proteins for use in characterizing and/or sequencing a polymer or for use as molecular sensors.
Public/Granted literature
- US20180312551A1 MODIFIED ALPHA HEMOLYSIN POLYPEPTIDES AND METHODS OF USE Public/Granted day:2018-11-01
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