Invention Grant
- Patent Title: Compositions and methods for producing high secreted yields of recombinant proteins
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Application No.: US15920331Application Date: 2018-03-13
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Publication No.: US10906947B2Publication Date: 2021-02-02
- Inventor: Joshua Kittleson , Thomas Stevens , Rena Hill , Carlos Gustavo Pesce
- Applicant: Bolt Threads, Inc.
- Applicant Address: US CA Emeryville
- Assignee: Bolt Threads, Inc.
- Current Assignee: Bolt Threads, Inc.
- Current Assignee Address: US CA Emeryville
- Agency: Goodwin Procter LLP
- Main IPC: C12N1/15
- IPC: C12N1/15 ; C12N15/81 ; C12P21/02 ; C07K14/46 ; C07K19/00 ; C07K14/435 ; C07K14/395
Abstract:
The present disclosure relates to methods for producing recombinant proteins, as well as compositions used in and produced by such methods. Specifically, the present disclosure relates to methods for producing high secreted yields of recombinant proteins, and the compositions provided herein include recombinant host cells that comprise polynucleotide sequences encoding proteins operably linked to at least 2 distinct secretion signals.
Public/Granted literature
- US20180282381A1 COMPOSITIONS AND METHODS FOR PRODUCING HIGH SECRETED YIELDS OF RECOMBINANT PROTEINS Public/Granted day:2018-10-04
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